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Fig. 1 | Biology Direct

Fig. 1

From: Antitumoral effects of Bortezomib in malignant mesothelioma: evidence of mild endoplasmic reticulum stress in vitro and activation of T cell response in vivo

Fig. 1

Effect of Bor on growth and death of MM cells. a The growth of human (MM-F1, MM-B1, H-Meso-1) and mouse (#40a) cell lines was assessed by the SRB assay after 24, 48 and 72 h of treatment with Bor or DMSO. The percentage of cell growth of Bor-treated cultures was calculated by normalizing their O.D. value to that of DMSO control cultures. The results are expressed as mean ± standard deviation (SD) of three independent experiments performed in triplicate (˟p ≤ 0.05; *p ≤ 0.01; #p ≤ 0.001 vs. DMSO). b Trypan blue exclusion assay was performed to determine the cell death percentage of human and mouse MM cells treated with Bor or DMSO for 24, 48, and 72 h. The results are expressed as the mean ± SD values of three independent experiments performed in triplicate (˟p ≤ 0.05; *p ≤ 0.01, #p ≤ 0.001 vs. DMSO)

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