About the dark corners in the gene function space of Escherichia coli remaining without illumination by scientific literature

Table 1 The number of E. coli K-12 genes as well as sum of literature score in various FPE score ranges

FPE score range	#Genes	Percentage of 4273 genes (%)	Literature score	Percentage of total score (%)	ƩGenes	Category
0	176	4.12	0.00	0.00	176	Not studied
0 < x < 1	692	16.19	231.95	0.14	2190	Very understudied
1 ≤ x < 5	967	22.63	2484.55	1.45
5 ≤ x < 10	531	12.43	3896.38	2.27
10 ≤ x < 15	322	7.54	3980.72	2.32	719	Understudied
15 ≤ x < 20	221	5.17	3833.54	2.23
20 ≤ x < 25	176	4.12	3945.99	2.30
25 ≤ x < 30	153	3.58	4202.54	2.45	372	Moderately studied
30 ≤ x < 35	112	2.62	3639.35	2.12
35 ≤ x < 40	107	2.50	3962.86	2.31
40 ≤ x < 45	65	1.52	2758.66	1.61	357	Intensively studied
45 ≤ x < 50	72	1.68	3440.15	2.00
50 ≤ x < 75	220	5.15	13,442.13	7.83
75 ≤ x < 100	117	2.74	10,031.58	5.85	459	Very intensively studied
100 ≤ x < 500	299	7.00	56,145.26	32.72
x ≥ 500	43	1.01	55,594.34	32.40
Total	4273	–	171,590	–	4273	–

This table presents the results of the automated mapping of publications onto the K-12 MG1655 genome. We list the total number of genes in the respective FPE range at the time of study (“#Genes”). We added a row for the 176 genes not specifically mentioned in any article about E. coli. Also, we calculated the sum of the literature score for all genes in the respective FPE range (“Literature Score”). The total literature score is equivalent to the total number of articles identified in this study. The FPE score range is further classified into six categories and the total number of genes in that category is provided (“ΣGenes”)

ISSN: 1745-6150