Fig. 6
From: Dual-labeled nanoparticles based on small extracellular vesicles for tumor detection
In vivo and ex vivo assessment of dual-sEVs by nuclear techniques. A Blood half-life. B Ex vivo biodistribution of dual-sEVs in a U87 xenograft mouse model 24 h after tracer injection. Detailed radioactivity in the brain (control organ) compared to U87 tumor tissue. * p < 0.05. C Ratio of dual-SEV uptake in U87 tumor tissue to non-target tissues at 24 h. D Excretion profile of dual-sEVs in urine and feces collected from the animal 24 h post-injection. Radioactivity in tissues is expressed as % ID/g. Data are represented as mean ± SD