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Fig. 2 | Biology Direct

Fig. 2

From: A functional reference map of the RNF8 interactome in cancer

Fig. 2

Identification and functional analysis of RNF8-interacting proteins. A The RNF8-interacting proteins complexes were obtained by two different co-IP assays (co-IP using anti-Flag antibody, the elution was then used to perform another round of co-IP using anti-HA antibody; co-IP using anti-RNF8 antibody). Gene ontology (GO) annotation analysis, KEGG pathway, and WikiPathway enrichment analysis were performed and visualized using R package “clusterprofiler” version 4.0. B GO molecular functions annotation, C GO biological processes annotation. D GO cellular components annotation. E Network connection of enriched KEGG pathways. F WikiPathway enrichment. The top-8 enriched items were shown in the network plot

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