Fig. 7From: Rab32 uses its effector reticulon 3L to trigger autophagic degradation of mitochondria-associated membrane (MAM) proteinsModel for Rab32-Mediated MAM-phagy. Activation of Rab32 triggers its interaction with the RTN3L effector. This promotes the selective autophagy of MERC-localized proteins, biochemically isolated as MAMs, and results in the degradation of TMX1, FACL4, and RTN3L itself. Rab32-mediated autophagy of MAMs requires the presence of PACS-2 and Mfn2Back to article page