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Fig. 3 | Biology Direct

Fig. 3

From: High-fat diet impairs ferroptosis and promotes cancer invasiveness via downregulating tumor suppressor ACSL4 in lung adenocarcinoma

Fig. 3

ACSL4 positively regulated ferroptosis in lung adenocarcinoma. a Gene set enrichment analysis (GSEA) revealed that oxidative stress-related genes were enriched in the high ACSL4 group. b The null distribution of the genes in the oxidative stress gene set. The false discovery rate was 22.4 % and the p value was 0.02. c Relationship between ACSL4 and genes in ferroptotic cell death signaling pathways by KEGG pathway enrichment analysis. The median ACSL4 expression level was used to separate the high and low expression of ACSL4 patients

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Biology Direct

ISSN: 1745-6150

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