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Table 6 Enrichment of DILI concern classes of compounds in low-risk category in comparison with high risk category

From: Integration of human cell lines gene expression and chemical properties of drugs for Drug Induced Liver Injury prediction

Method

Enrichment

 

no DILI

Ambiguous

less DILI

most DILI

Best single result

1.94

1.01

0.74

0.70

Mean of all results

2.32

0.82

0.65

0.96

Mean of 5 best results

3.95

0.77

0.59

0.78

Linear combination

2.81

0.86

0.65

0.71

Random Forest

2.93

0.82

0.69

0.70