Fig. 5
From: Prediction and mechanistic analysis of drug-induced liver injury (DILI) based on chemical structure
Precision and percentage coverage of significant DILI-related structural alerts (SAs) (p-value ≤0.05). The maximum coverage of SAs was 77.6% (benzene derivative generated by SARpy), however the average coverage was much lower - 6.68%. All MoSS-derived SAs had a precision of 1, the precision of SARpy SAs was lower on average but still relatively high - mean precision 0.85, and literature-derived alerts had a mean precision of 0.88