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Fig. 1 | Biology Direct

Fig. 1

From: Ablation of Fam20c causes amelogenesis imperfecta via inhibiting Smad dependent BMP signaling pathway

Fig. 1

Reduced expressions of FAM20C in the Sox2-Cre;Fam20Cfl/fl mice. A and B, IHC analyses (signal in brown) of FAM20C on the sagittal sections of the mandibular incisors of 7-day-old Fam20cfl/fl (A) and Sox2-Cre;Fam20cfl/fl mice (B). a1, a2, a3, a4, b1, b2, b3 and b4 are the higher magnification views of the preameloblasts in blue boxes, the presecretory ameloblasts in red boxes, the secretory ameloblasts in purple boxes, the maturation ameloblasts in green boxes in A and B, respectively. FAM20C was absent in the incisors of Sox2-Cre;Fam20cfl/fl mouse. Scale bars: 500 μm in A and B; 20 μm in a1, a2, a3, a4, b1, b2, b3 and b4. (E: Enamel; D: dentin; Am: Ameloblast; Od: Odontoblast)

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