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Fig. 1 | Biology Direct

Fig. 1

From: Long non-coding RNA LINC00426 contributes to doxorubicin resistance by sponging miR-4319 in osteosarcoma

Fig. 1

Expression level of LINC00426 in OS closely correlated with doxorubicin resistance and clinical outcomes. a The RNA level of LINC00426 in the three pairs of doxorubicin-resistant (DXR) and doxorubicin-sensitive (Parental) OS cell lines was detected by qRT-PCR. b qRT-PCR analysis of LINC00426 RNA level in 50 normal adjacent tissues and osteosarcoma tumors (shown as 2-ΔΔCT). c LINC00426 expression significantly increased in specimens of OS patients who were doxorubicin-resistant (DXR, n = 24) compared to those who were doxorubicin-sensitive (DXS, n = 26). d Kaplan-Meier survival rates for OS patients with low (n = 25) and high (n = 25) LINC00426 expression. Log-rank test for D, Student’s t-tests for others. *P < 0.05; **P < 0.01; ***P < 0.001

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