Fig. 2

Expression profiles of PRKCG across normal, LGG and GBM samples. PRKCG expression profiles were compared between glioma and normal samples (D3-GSE16011-E in panel a [RMA normalized], V1-GSE4290-E in panel b [MAS5 normalized], V2-GSE50161-E in panel c[gcRMA normalized], V3-GSE59612-E in panel d, V4-GSE111260-E in panel e [RMA normalized], V5-GSE2223-E in panel f [Lowess normalized]), between different anatomic regions (V6-Ivy GAP-E in panel g), and between GBM and LGG samples (D4-TCGA-E in panel h, V1-GSE4290-E in panel i [MAS5 normalized] and V7-CGGA-E in panel j [Lowess normalized]). All the normalization methods labeled above were derived from and detailed in their corresponding publications, and all these datasets were made publicly accessible at ftp://download.big.ac.cn/glioma_data/. The Wilcoxon tests were performed and the statistical significance levels were coded by: ns p > 0.05, * p < 0.05, ** p < 0.01 and *** p < 0.001