Table 4 Values of rate and effect parameters
Symbol | Value | Unit | Explanation |
|---|---|---|---|
c0 | 0.08 | – | Relative glucose content in the DMI |
c1 | 0.08 | – | Fraction of directly absorbable glucose |
c2 | 84211 | mU/(L ·d) | Rate constant for insulin secretion |
c3 | 2105 | 1/d | Rate constant for insulin degradation |
c4 | 70182 | ng/(L ·d) | Rate constant for glucagon secretion |
c5 | 350.87 | 1/d | Rate constant for glucagon degradation |
c6 | 50 | (g ·L)/(mU ·d) | Rate constant for glucose absorption from blood into liver cells |
c7 | 180 | L/(mU ·d) | Rate constant for glycogenesis |
c8 | 0.22683 | L/(mU ·d) | Rate constant for lipogenesis |
c9 | 1350 | (g ·L)/(ng ·d) | Rate constant for glycogenolysis |
c10 | 3.5272 | (g ·L)/(ng ·d) | Rate constant for gluconeogenesis |
c11 | 0.0684 | L/(ng ·d) | Rate constant for glucose release from the liver to the blood |
c12 | 1000 | g/d | Glucose usage for maintenance |
c13 | 72 | g/kg | Glucose usage for milk production |
c14 | 5 | 1/d | Glucose usage for liver metabolism |
c17 | 0.4 | [IGF]/d | Basal IGF-1 synthesis rate in the blood |
c18 | 1 | [IGF]/d | P4- and insulin-regulated IGF-1 synthesis rate |
c19 | 1.7 | 1/d | IGF-1 clearance rate |
c20 | 3.49 | 1/d | Maximum effect of LH on follicular function |
c21 | 1 | [LH] | Maximum threshold of LH to stimulate follicular function |
c22 | 3 | – | Maximum effect of insulin on FSH synthesis in the pituitary |
c23 | 1.05 | – | Maximum effect of insulin on LH synthesis in the pituitary |
c24 | 1.5 | [Oxy]/d | Maximum rate of additional oxytocin synthesis during lactation |
c25 | 0.0007 | 1/d2 | Clearance of additional oxytocin during lactation |
V | 22.8 | L | Extracellular volume of blood |