Predicting survival times for neuroblastoma patients using RNA-seq expression profiles

Biology Direct

Table 3 Pathway enrichment analysis of genes selected by the G-4, T-4, and TI-4 models

Outcome	Pathway	Count	Size	P-value	BH
OS	ErbB signaling pathway	11	60	0.029	0.999
OS	Salivary secretion	6	23	0.042	0.995
OS	Inflammatory mediator regulation of TRP channels	9	48	0.049	0.983
EFS	Terpenoid backbone biosynthesis	4	8	0.010	0.906
EFS	Metabolic pathways	29	304	0.016	0.847
EFS	Valine, leucine and isoleucine degradation	5	20	0.032	0.911
EFS	Biosynthesis of antibiotics	12	98	0.037	0.882
EFS	Fatty acid metabolism	5	21	0.037	0.820

In this analysis, the GeneCards genes are used at the background. The columns include survival outcome (OS or EFS), KEGG pathway name, the number of genes in the gene set that are in the pathway, the total number of genes annotated for the pathway, the p-value from a modified fisher’s exact test, and the Benjamini-Hochberg corrected p-value

ISSN: 1745-6150