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Table 3 Pathway enrichment analysis of genes selected by the G-4, T-4, and TI-4 models

From: Predicting survival times for neuroblastoma patients using RNA-seq expression profiles

Outcome Pathway Count Size P-value BH
OS ErbB signaling pathway 11 60 0.029 0.999
OS Salivary secretion 6 23 0.042 0.995
OS Inflammatory mediator regulation of TRP channels 9 48 0.049 0.983
EFS Terpenoid backbone biosynthesis 4 8 0.010 0.906
EFS Metabolic pathways 29 304 0.016 0.847
EFS Valine, leucine and isoleucine degradation 5 20 0.032 0.911
EFS Biosynthesis of antibiotics 12 98 0.037 0.882
EFS Fatty acid metabolism 5 21 0.037 0.820
  1. In this analysis, the GeneCards genes are used at the background. The columns include survival outcome (OS or EFS), KEGG pathway name, the number of genes in the gene set that are in the pathway, the total number of genes annotated for the pathway, the p-value from a modified fisher’s exact test, and the Benjamini-Hochberg corrected p-value