Skip to main content

Table 1 Summary of Kaplan-Meier estimates for 2-year OS and 2-year EFS for clinically high-risk patients using each of the 18 proposed models

From: Predicting survival times for neuroblastoma patients using RNA-seq expression profiles

  

LPS

  

non-LPS

    

Outcome

Prob

SE

N

Prob

SE

N

Data

Model

P-value

OS

0.57

0.09

31

0.79

0.05

59

Null model

 

0.574

OS

0.60

0.07

57

0.91

0.05

33

G

1

0.081

OS

0.60

0.06

60

0.93

0.05

30

G

2

0.082

OS

0.55

0.09

29

0.79

0.05

61

G

3

0.166

OS

0.50

0.10

24

0.79

0.05

66

G

4

0.164

OS

0.57

0.07

55

0.94

0.04

35

T

1

0.128

OS

0.56

0.07

47

0.88

0.05

43

T

2

0.002

OS

0.41

0.12

17

0.78

0.05

73

T

3

0.048

OS

0.57

0.09

33

0.79

0.05

57

T

4

0.081

OS

0.61

0.07

56

0.88

0.06

34

I

1

0.124

OS

0.51

0.08

36

0.85

0.05

54

I

2

0.027

OS

0.47

0.10

25

0.81

0.05

65

I

3

0.137

OS

0.43

0.10

25

0.82

0.05

65

I

4

0.017

OS

0.57

0.07

56

0.94

0.04

34

TI

1

0.092

OS

0.54

0.07

49

0.90

0.05

41

TI

2

0.001

OS

0.40

0.11

21

0.81

0.05

69

TI

3

0.036

OS

0.40

0.11

22

0.80

0.05

68

TI

4

0.009

OS

0.42

0.10

25

0.82

0.05

65

Ensemble

 

0.016

EFS

0.39

0.08

37

0.36

0.07

53

Null model

 

0.616

EFS

0.35

0.07

53

0.39

0.08

37

G

1

0.299

EFS

0.34

0.07

52

0.41

0.08

38

G

2

0.266

EFS

0.30

0.06

58

0.50

0.09

32

G

3

0.125

EFS

0.31

0.06

59

0.48

0.09

31

G

4

0.125

EFS

0.29

0.06

62

0.56

0.10

28

T

1

0.036

EFS

0.35

0.07

51

0.40

0.08

39

T

2

0.946

EFS

0.29

0.07

38

0.43

0.07

52

T

3

0.065

EFS

0.31

0.07

47

0.43

0.08

43

T

4

0.150

EFS

0.35

0.06

66

0.43

0.10

24

I

1

0.256

EFS

0.35

0.06

66

0.43

0.10

24

I

2

0.256

EFS

0.29

0.07

43

0.45

0.07

47

I

3

0.052

EFS

0.29

0.07

42

0.44

0.07

48

I

4

0.082

EFS

0.31

0.06

57

0.47

0.09

33

TI

1

0.084

EFS

0.33

0.06

68

0.50

0.11

22

TI

2

0.183

EFS

0.29

0.07

42

0.45

0.07

48

TI

3

0.062

EFS

0.30

0.07

44

0.44

0.08

46

TI

4

0.085

EFS

0.36

0.06

58

0.39

0.09

32

Ensemble

 

0.599

  1. Patients with predicted survival of less than 2 years are labeled as Low Predicted Survival (LPS), and otherwise are non-LPS. Columns labeled “Prob.”, “SE”, and “N” correspond to the estimated probability of 2-year survival, the standard error of the estimate, and the number of patients in the given cohort. The P-values are for the logrank test comparing LPS to non-LPS survival. The “Data” column refers to the type of RNA-seq data used, and the “Model” column refers to the dimension reduction technique used