Fig. 1From: COGcollator: a web server for analysis of distant relationships between homologous protein familiesThe first part of the COGcollator pipeline. An HMM (hidden Markov model) profile is constructed for each of the 4534 COGs using a subset of sequences that should belong to a particular COG and satisfy two additional conditions, see the main text for details. See Fig. 2 for the detailed description of the step of profile HMM searchBack to article page