Fig. 1From: The role of cell location and spatial gradients in the evolutionary dynamics of colon and intestinal cryptsSchematic of an intestinal crypt. The intestinal crypt consists of several different types of cells. At the base of the crypt, stem cells are found within the stem-cell niche, with the niche formed by the stem cells themselves and mesenchymal cells that surround the crypt base. At the top of the crypt, there are fully differentiated cells, and between the bottom and the top of the crypt there are transit amplifying cellsBack to article page