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Table 2 Probable functional associations recognised for potential nucleotide cyclases

From: Computational recognition and analysis of hitherto uncharacterized nucleotide cyclase-like proteins in bacteria

Sr. No. UniProt ID Gene name Potential interacting partner Pfam domain of the interacting partner [Pfam ID] Gross function of the interacting partner
1. R4MJ84 J113_17860 J113_17870 Cyclic nucleotide-binding domain [PF00027] Signal transduction, regulatory processes
2. R4MJ84 J113_17860 J113_17875 Cyclic nucleotide-binding domain [PF00027] Signal transduction, regulatory processes
3. J9WHW1 MIP_02960 MIP_02970 Periplasmic binding protein [PF13458] Signal transduction, transport
4. J9WHW1 MIP_02960 MIP_02959 Alpha/beta hydrolase domain [PF12697] Metabolic processes
5. U5WU67 MKAN_22035 MKAN_22050 Alpha/beta hydrolase domain [PF12697] Metabolic processes
6. B2HFJ8 MMAR_1384 MMAR_1388 Alpha/beta hydrolase domain [PF12697] Metabolic processes
7. B2HFJ8 MMAR_1384 MMAR_1378 Helix-turn-helix domain [PF01381] Regulatory processes
8. P9WL98 MT2638 MT2640 Cyclic nucleotide-binding domain [PF00027] Signal transduction, regulatory processes
9. P9WL98 MT2638 MT2641 Cyclic nucleotide-binding domain [PF00027] Signal transduction, regulatory processes
10. A0PR68 MUL_2491 MUL_2488 Alpha/beta hydrolase domain [PF12697] Metabolic processes
11. A0PR68 MUL_2491 MUL_2497 Helix-turn-helix domain [PF01381] Regulatory processes
12. L7V7X7 MULP_01555 MULP_01559 Alpha/beta hydrolase domain [PF12697] Metabolic processes
13. L7V7X7 MULP_01555 MULP_01549 Helix-turn-helix domain [PF01381] Regulatory processes
14. H8ITY9 OCU_21180 OCU_21250 Periplasmic binding protein [PF13458] Signal transduction, transport
15. H8ITY9 OCU_21180 OCU_21170 Alpha/beta hydrolase domain [PF12697] Metabolic processes
16. S4Z758 OEM_18810 OEM_18800 Alpha/beta hydrolase domain [PF12697] Metabolic processes
17. P9WL99 Rv2561 Rv2564 Cyclic nucleotide-binding domain [PF00027] Signal transduction, regulatory processes
18. P9WL99 Rv2561 Rv2565 Cyclic nucleotide-binding domain [PF00027] Signal transduction, regulatory processes
19. I2ACB6 W7S_09825 W7S_09820 Alpha/beta hydrolase domain [PF12697] Metabolic processes
20 W8FCI6 HSW_3800 HSW_3799 Phosphohydrolase [PF01966] Nucleic acid metabolism, signal transduction