From: The human disease network in terms of dysfunctional regulatory mechanisms
 |  | Disease pairs correlated to known disease genes or drugs |  | ||
---|---|---|---|---|---|
 |  | DDLs | Non-DDLs | Total | P-value of Fisher’s Exact test |
Disease pairs sharing disease genes | Significant | 910 (81Â %) | 2911 (78Â %) | 3821 | 0.009085a |
Non-significant | 209 (19Â %) | 821 (22Â %) | 1030 | Â | |
 | Total | 1119 | 3732 |  |  |
Disease pairs sharing disease drugs | Significant | 348 (47Â %) | 1095 (42Â %) | 1443 | 0.02307a |
Non-significant | 397 (53Â %) | 1481 (58Â %) | 1881 | Â | |
 | Total | 745 | 2576 |  |  |