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Figure 2 | Biology Direct

Figure 2

From: The eukaryotic translation initiation regulator CDC123 defines a divergent clade of ATP-grasp enzymes with a predicted role in novel protein modifications

Figure 2

Evolutionary relationship of three families of the R2K ATP-grasp module shown to the left and conserved contextual associations including operonic organizations and domain architectures are provided on the right. Tree nodes supported by bootstrap >75% are shown. Proteins are denoted by their GenBank index numbers and their complete species names and colored according to their lineages: bacterial in blue, viral in green, amoeboazoan in orange, Naegleria in purple, fungal in red. Conserved gene neighborhoods are depicted as boxed, labeled arrows with the arrowhead pointing to the C-terminus of the protein. Genes known to be part of the T6SS are shaded in gray, including the “T6SS.unk” gene containing a domain of unknown function in the secretion system. Conserved domain architectures are depicted as adjoining, labeled shapes.

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Biology Direct

ISSN: 1745-6150

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