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Figure 2 | Biology Direct

Figure 2

From: Test on existence of histology subtype-specific prognostic signatures among early stage lung adenocarcinoma and squamous cell carcinoma patients using a Cox-model based filter

Figure 2

Study schema showing how the 29-, 32-, and 26-gene signatures were obtained. The 29-gene signature was obtained using all DEG genes; the 32-gene signature was obtained using 1889 genes with extra barcode-frequency filtering and actual expression values of these genes; and the 26-gene signature was obtained using the barcode values of those 1889 genes. We used both PCA procedure and the models with all genes as covariates to compute the risk scores and found out that even the proportion in variance of variables is higher than 95% by the selected PCs, the performance is inferior than that using all selected genes as covariates.

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