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Figure 1 | Biology Direct

Figure 1

From: Test on existence of histology subtype-specific prognostic signatures among early stage lung adenocarcinoma and squamous cell carcinoma patients using a Cox-model based filter

Figure 1

Scenarios of the Cox-model filter and their interpretation. β2 and β3 are the coefficients for the gene term and gene × subtype interaction term in Equation 1, and they are the parameters of interest. Ideally, non-overlap of genes fitting case B and those fitting case E suggests existence of mutually exclusive subtype-specific prognostic genes. Character A-G represent different situations (or cases) for the proposed model.

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