Figure 2
From: Synthetic lethals in HIV: ways to avoid drug resistance
Venn representation of the interdependent pairs in the RT protein. All variant pairs of residues close in space and at the surface of the protein were examined using five statistical tests. Black numbers stand for the results from non-treated set. Red numbers represent the results from treated set of patients. χ2, D’, r2 and Fisher’s are statistical tests explained in MM. BLD is a background linkage disequilibrium described in MM. The shaded area corresponds to the pairs of interdependent residues, having 3 valid statistical tests out of 4 and a BLD score > 2.