Similar protein interactions between human and yeast counterparts. Known and predicted protein interactions were retrieved from IntAct  and BioGrid  using both human and yeast gene names as query terms. Interactions were organized and edited following suggestions by Lim et al. . It is interesting to note that although a sizeable portion of predicted interactors are also predicted to have functional orthology between species, very few of the inter-protein interactions among predicted orthologs were reported for both species.