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Table 2 Disease-related enrichment analysis of H. sapiens proteins involved in host-pathogen PPIs

From: Stringent homology-based prediction of H. sapiens-M. tuberculosis H37Rv protein-protein interactions

Gene list Overlap p-value
 (a)
Early Changers 32 1.022E-10
Late Changers 31 3.785E-14
Consistent Changers 35 1.500E-14
Early and Late Changers 56 6.996E-21
Early and Consistent Changers 49 3.721E-18
Consistent and Late Changers 42 1.499E-16
Macrophages and dendritic differentially expressed genes 107 2.097E-34
 (b)
Early Changers 6 3.08E-02
Late Changers 6 6.11E-03
Consistent Changers 8 1.04E-03
Early and Late Changers 10 2.94E-03
Early and Consistent Changers 9 4.30E-03
Consistent and Late Changers 9 1.07E-03
Macrophages and dendritic differentially expressed genes 35 5.23E-14
  1. This table summarizes H. sapiens proteins’ (involved in the predicted host-pathogen PPIs) enrichment (over-representation) in M. tuberculosis H37Rv infection and treatment-related differentially expressed gene lists.
  2. (a) is enrichment analysis results from the stringent homology-based approach.
  3. (b) is enrichment analysis results from the conventional homology-based approach.