Impairment of translation in neurons as a putative causative factor for autism

Biology Direct

Table 3 Jackknife analysis of the rare synonymous variations in genes associated with ASD (the AV set)

Number of removed AVs	Mean P(S_H≤ S_H_r)	Standard error	Fraction of cases with P(S_H≤ S_H_r) ≤ 0.05
10	0.0031	0.0004	0.988
20	0.0233	0.0007	0.939
26 (corresponds to the common SNP dataset)	0.0279	0.002	0.886
30	0.0323	0.002	0.839
40	0.0451	0.003	0.718

Codon frequencies for the brain-specific genes were estimated by Semon and co-workers [47].

ISSN: 1745-6150