Figure 6

Stabilities of unique lincRNAs in PH or ENCODE. LincRNA decay curves after blocking transcription in K562 with actinomycin D and measuring relative levels of lincRNA remaining relative to a control gene (GAPDH) by qPCR. The relative quantitative values at time 0 h were arbitrarily adjusted to 100%. The fitted curve was modeled using locally weighted polynomial regression (LOESS method). Results are from three biological replicates, and Error bars show standard deviation [(**) P < 0.01; (*) P <0.05, Student’s t-test].