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Figure 8 | Biology Direct

Figure 8

From: Input-output relations in biological systems: measurement, information and the Hill equation

Figure 8

Greater failure rates for reactions reduce sensitivity to low input and increase the Hill coefficient, k . The curves arise from the same analysis as Figure 7, in which the curves from left to right are associated with an increase in the maximum failure rate as a=0.2,0.4,0.6. The curves in this figure have n=8 reactions in the cascade, a gain of g=1.5, and a decline in failure with increasing input, b=10. The scale for the input signal is normalized so that each curve has a final output of 0.85 at a normalized input of one.

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