Skip to main content

Table 3 Evolved proto-codes, optimal solutions

From: Amino acid fermentation at the origin of the genetic code

Amino Acid

# anticodons (SE)

G+U content (SE)

p*

p +

Alanine

2.21(0.84)

1.98 (0.89)

10-8

10-21

Glycine

13.06 (2.96)

1.36 (0.66)

10-7

10-9

Aspartic Acid

14.24 (3.01)

1.25 (0.68)

10-17

10-23

Valine

2.19 (0.94)

2.23 (0.54)

10-25

10-37

Leucine

10.77 (4.60)

1.41 (0.61)

0.0024

10-7

Glutamic acid

2.09 (0.89)

2.18 (0.46)

10-29

10-28

Serine

2.13 (0.86)

2.15 (0.52)

10-21

10-27

Isoleucine

2.13 (1.12)

2.18 (0.54)

10-22

10-30

Proline

13.30 (3.04)

1.37 (0.69)

0.00003

10-6

Threonine

1.88 (1.16)

2.12 (0.56)

10-18

10-21

  1. Outcomes of selection on the fermentation yield of proto-codes randomly initiated with equal probabilities of glycine and alanine. Every 7000 generations a new amino acid was added, randomly selected from the remaining Miller amino acids. Overall, the simulations ran for 100,000 generations (MC steps). The results are from 97 optimal codes (see Figure 10). * Significance p value for a sign test; + Significance p value for a χ2 test. Otherwise as in Table 2.
Back to article page

Biology Direct

ISSN: 1745-6150

Contact us