Figure 5
From: Early evolution of efficient enzymes and genome organization
The evolution of mean flux (both direct and waste) in a 3-step reaction network. Both fluxes were normalized (the unity corresponds to the optimal enzyme configuration). Mean flux is determined every 103 time steps. The model was run for 5·105 time steps, results for the first 2·105 time steps are shown. All replicate populations reached the fully specialized state in equilibrium. Other parameters are as in Figure 2.