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Table 7 Agreement between the model and experiment for euthyroid and hypothyroid rats

From: Modeling RNA polymerase interaction in mitochondria of chordates

LSP HSP mTERF R L 1 n Transcription levels in hypothyroid rat relative to euthyroid one in the model (upper) and experiment (lower)
COX1 ATP6/8 COX3 ND4 ND5 CYTB
0.1056 0.0721 0.9453 30.605 1.736 0.666 0.641 0.646 0.622 0.614 0.613
0.1056 0.0336 0.9453 30.637   0.61 0.33 0.33 0.61 0.78 0.35
Error (if statistically independent): ±0.35 (0.2) ±0.17 (1.9) ±0.17 (1.9) ±0.34 (0.0) ±0.42 (0.6) ±0.17 (1.5)
Error (if statistically dependent): ±0.79 (0.1) ±0.39 (0.8) ±0.39 (0.8) ±0.79 (0.0) ±0.97 (0.2) ±0.39 (0.7)
Deviation from the experiment,%: +9 +94 +96 +2 −21 +75
  1. Inferences are obtained under the polymerase elongation rate of 500 nt/s and the values of p, q estimated for the frog.
  2. Upper left part: the solutions for the euthyroid (upper row) and hypothyroid (lower row) rats. Variables and predicted values are in bold. Note that HSP = HSP1 + HSP2.
  3. The right part: experimental data and model predictions. Experimental errors were estimated for both cases of statistically independent measurements and counter assumption. In the latter case, the model results are within experimental error. Differences between model and experimental estimates are shown in parentheses in the error radius units.