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Table 4 Agreement between the model and experiment for three frog specimens

From: Modeling RNA polymerase interaction in mitochondria of chordates

time

mTERF

LSP1

ND1

COX2

ATP6/8

ND4

ND6

CYTB

 

Frog1

 

mod

exp

dev

mod

exp

dev

mod

exp

dev

mod

exp

dev

mod

exp

dev

mod

exp

dev

Egg

0.0157

0.0034

1.0

1.0

 

1.0

1.0

 

1.0

1.0

 

1.0

1.0

 

1.0

1.0

 

1.0

1.0

 

+5 h

0.0448

0.0089

1.0

1.1

−12

0.9

0.8

+14

0.9

0.9

+1

0.9

2.1

−59

2.4

2.4

−1

0.8

0.7

+19

+10 h

0.0872

0.0157

1.2

1.3

−5

1.1

1.1

+1

1.1

0.7

+56

1.0

2.3

−57

4.1

4.0

+2

0.9

0.6

+50

+14 h

0.0793

0.0173

1.7

2.3

−26

1.6

1.6

−3

1.5

1.3

+18

1.4

3.0

−53

4.4

4.4

0

1.2

1.2

+3

+16 h

0.0960

0.0209

2.0

2.9

−31

1.7

1.4

+24

1.7

1.3

+31

1.5

4.3

−65

5.6

5.8

−4

1.3

1.3

+2

+18 h

0.0542

0.0157

2.1

3.2

−34

1.9

1.7

+14

1.9

1.9

+1

1.8

4.5

−60

4.4

4.2

+4

1.6

1.3

+25

+20 h

0.0655

0.0157

1.8

3.0

−41

1.6

1.4

+13

1.6

1.8

−12

1.5

4.6

−68

4.2

4.2

0

1.3

1.2

+8

+23 h

0.0721

0.0492

9.4

9.7

−4

7.6

5.1

+49

7.4

6.5

+14

6.4

16.1

−60

12.9

12.2

+5

5.3

5.2

+2

+48 h

0.0542

0.0872

29.3

26.6

+10

26.2

13.4

+96

26.0

26.1

0

23.8

60.3

−61

18.6

18.6

0

20.2

23.4

−14

+96 h

0.0407

0.0960

48.1

48.7

−1

45.3

20.9

+117

45.4

48.3

−6

43.3

104.2

−58

16.7

17.4

−4

38.8

39.3

−1

time

mTERF

LSP1

ND1

COX2

ATP6/8

ND4

ND6

CYTB

 

Frog2

 

mod

exp

dev

mod

exp

dev

mod

exp

dev

mod

exp

dev

mod

exp

dev

mod

exp

dev

Egg

0.0089

0.0041

1.0

1.0

 

1.0

1.0

 

1.0

1.0

 

1.0

1.0

 

1.0

1.0

 

1.0

1.0

 

+6 h

0.0045

0.0023

1.2

1.3

−8

1.2

1.0

+22

1.2

1.3

−5

1.2

1.4

−12

0.7

0.7

+6

1.2

1.2

+3

+9 h

0.0073

0.0045

1.3

1.5

−14

1.3

1.3

−1

1.3

1.2

+8

1.3

1.6

−19

1.1

1.1

+1

1.3

1.3

−1

+20 h

0.0157

0.0157

3.8

4.6

−17

3.7

3.7

+1

3.7

3.7

+1

3.7

3.7

0

2.8

2.8

−2

3.6

4.0

−11

+30 h

0.0157

0.0230

7.2

7.2

0

7.1

6.8

+4

7.1

8.1

−13

7.0

6.2

+14

3.7

3.7

0

6.8

8.1

−17

+48 h

0.0407

0.1056

20.5

19.5

+5

19.7

19.7

0

19.6

28.7

−32

19.1

17.7

+8

8.6

8.4

+2

17.3

23.1

−25

+7 days

0.0041

0.0073

6.5

6.1

+7

6.6

8.0

−18

6.6

8.5

−22

6.7

4.9

+36

2.4

2.3

+3

6.6

6.6

+1

time

mTERF

LSP1

16 S

ND6

            
 

Frog3

 

mod

exp

dev

mod

exp

dev

            

Egg

0.0960

0.0026

1.0

1.0

 

1.0

1.0

             

+5 h

0.0407

0.0050

2.2

2.2

+0.9

2.2

2.2

0.0

            

+14 h

0.0230

0.0081

5.0

5.0

0.0

4.5

4.5

−0.2

            

+20 h

0.0038

0.0028

5.9

6.0

−1.3

4.0

4.0

+0.5

            

+28 h

0.0336

0.1056

92.2

92.0

+0.2

25.1

25.0

+0.4

            

+48 h

0.0143

0.0306

44.1

44.0

+0.2

15.0

15.0

+0.3

            
  1. In columns: “time” gives absolute times of embryonic development; “mTERF“ and “ LSP1” are intensities of the mTERF factor binding with the termination site and cooperative binding with the promoter, respectively, under the polymerase rate of 500 nt/s; further columns are modeled (mod) and experimental (exp) gene transcription levels and their relative deviations (dev) obtained with equation (9). Variables are in bold.