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Table 6 Selected common pathways between van de Vijver and Wang datasets (all enriched for breast cancer non-metastasis; bold for those enriched for metastasis)

From: Pathway-based classification of cancer subtypes

Common pathways for non-metastasis (or metastasis in bold) Function of pathway
HSA04610_COMPLEMENT_AND_COAGULATION_CASCADES Coagulation inhibits lung cancer metastasis in animal studies [54] A part of innate immune system and an effector of antibody-mediated immunity [55]
HSA00100_BIOSYNTHESIS_OF_STEROIDS Found in metastatic tissue [56] and related with feminizing syndromes [57]
HSA04110_CELL_CYCLE Related with cell growth and cell death