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Figure 4 | Biology Direct

Figure 4

From: Polymorphic toxin systems: Comprehensive characterization of trafficking modes, processing, mechanisms of action, immunity and ecology using comparative genomics

Figure 4

Features of PVC metallopeptidase toxins: (A) multiple sequence alignment, (B) predicted topology diagram, (C) representative domain architectures, and (D) conserved gene neighborhoods for PVC containing genes across different bacterial lineages and archaea. In (D), PVC toxins are shown in blue, the AAA + ATPase associated with the PVC system (PVC-AAA) in orange and phage-derived proteins in yellow. Gene neighborhoods are labeled with the corresponding information for the PVC-metallopeptidase containing genes marked with an asterisk. The labeling scheme for domain architectures and alignments, and the coloring scheme and consensus abbreviations are as in Figure 3.

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