Figure 1From: A novel virus genome discovered in an extreme environment suggests recombination between unrelated groups of RNA and DNA virusesOrganiztion of the BSL RDHV genome. (A) Schematic representations of tombusvirus, BSL RDHV and porcine circovirus (PCV) genomes: Tombusviruses are linear ssRNA viruses, BSL RDHV and PCV are circular ssDNA viruses. Bars below ORFs indicate protein families detected by InterProScan. (B) Comparison of PCV-1 and BSL RDHV stem-loops: Both BSL RDHV and circoviruses have a conserved stem-loop in the intergenic region upstream of Rep. Black text indicates sequence identity. Nonanucleotide replication origins in the 13nt loop are boxed. Brackets indicate the 9 nucleotide stem preceding hexamer repeats H1 and H2 (gray boxes).Back to article page