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Table 5 Distribution of pre-miRs containing TFBS (z-score ≥ 2.33) relative to nearby downstream genes.

From: Transcription factor binding sites are highly enriched within microRNA precursor sequences

  pre-miRs containing TFBS pre-miRs lacking TFBS
pre-miRs is upstream 29 85
pre-miRs is not upstream 89 496
  1. Pre-miRs containing TFBS are more likely to reside ≤ 5 kb upstream of nearby genes, and pre-miRs that lie upstream of nearby genes are more likely to contain TFBS (χ2 = 7.109, p = 0.008).