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Table 2 Conservation profile of pre-miRs containing conserved TFBS (z-score ≥ 2.33).

From: Transcription factor binding sites are highly enriched within microRNA precursor sequences

  

Lineage

  
 

Primate

Mammal

Vertebrate

Row total

Pre-miRs containing TFBS

9

40

69

118

Pre-miRs lacking TFBS

316

146

119

581

Column total

325

186

188

699

  1. "Primate" lineage indicated here includes miRNAs that have pre-miR homologues in non-primate species but which do not match the mature human miRNA sequence exactly. The lineage distribution is extremely different between pre-miRs that contain vs. those that lack TFBS (χ2 = 101.59, p = 0).
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Biology Direct

ISSN: 1745-6150

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