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Figure 1 | Biology Direct

Figure 1

From: On universal common ancestry, sequence similarity, and phylogenetic structure: the sins of P-values and the virtues of Bayesian evidence

Figure 1

Extreme value probability distribution for similarity scores. A standard extreme value distribution (EVD) is shown. In Karlin-Altschul statistics, similarity scores (S) for alignments of random sequences are assumed to follow an EVD. P-values are based on the tail probability, shown as the shaded blue area, corresponding to the probability of observing a similarity score greater than or equal to the observed similarity score (So) for a given alignment of interest.

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