Figure 3
From: Kinetics of the viral cycle influence pharmacodynamics of antiretroviral therapy
IC50 color-coded as a function of δ pre and k HIV . For a drug with m = 1 and kdrug = 100, the parameter regimes generally occupied by the various stages of the HIV viral life cycle in activated CD4+ T cells and macrophages (for more details, see Section 5 of Additional File 1) are outlined with a solid line and parameter regime potentially available through pharmacologic intervention approximated with a dashed line based on cell-specific properties.