Table 2 MicroRNAs associated (P < 0.05) with different genetic subtypes depicting chromosomal location.
From: MicroRNA expression in multiple myeloma is associated with genetic subtype, isotype and survival
Cytogenetic group | microRNA | Fold change | P -value | Chromosome |
|---|---|---|---|---|
IgH trans (n = 14) | miR-590 | 3.28 | 1.62E-02 | 7q11.23 |
miR-886 | 1.63 | 1.46E-02 | 5q31.1 | |
miR-33b | 1.48 | 2.46E-02 | 17p11.2 | |
miR-184 | -1.43 | 3.87E-02 | 15q25.1 | |
miR-139 | -1.44 | 1.47E-02 | 11q13.4 | |
miR-508 | -1.63 | 4.55E-03 | Xq27.3 | |
miR-579 | -1.66 | 2.43E-02 | 5p13.3 | |
t(11;14) (n = 8) | miR-202* | 2.16 | 3.10E-03 | 10q26.3 |
miR-520c | 2.05 | 1.26E-03 | 19q13.42 | |
miR-890 | 2.04 | 4.39E-02 | Xq27.3 | |
miR-582 | 1.91 | 4.06E-02 | 5q12.1 | |
miR-122a | 1.88 | 1.40E-02 | 3p21.31 | |
miR-526b* | 1.86 | 1.09E-04 | 19q13.42 | |
miR-375 | -1.74 | 2.04E-02 | 2q35 | |
miR-543 | -1.59 | 3.46E-02 | 14q33.21 | |
miR-650 | -1.58 | 4.00E-02 | 22q11.22 | |
miR-193a | -1.51 | 1.35E-02 | 17q11.2 | |
miR-147b | -1.46 | 2.76E-02 | 15q21.1 | |
miR-526a | -1.51 | 4.68E-02 | 19q13.42 | |
miR-542 | -1.56 | 1.81E-02 | Xq26.3 | |
miR-301 | -2.22 | 4.80E-02 | 17q22 | |
miR-26b | -2.62 | 3.81E-02 | 2q35 | |
miR-376a | -2.63 | 2.68E-02 | 14q33.21 | |
miR-21 | -2.82 | 5.19E-03 | 17q23.1 | |
t(4;14) (n = 3) | miR-376a | 3.48 | 1.23E-02 | 14q33.21 |
miR-574 | 3.11 | 1.23E-02 | 4p14 | |
miR-99a | 2.53 | 1.23E-02 | 21q21.1 | |
miR-214 | 2.12 | 2.77E-02 | 1q24.3 | |
miR-577 | 1.97 | 3.85E-02 | 4q26 | |
miR-342 | 1.79 | 3.50E-02 | 14q32.2 | |
miR-935 | -2.07 | 3.55E-02 | 19q13.42 | |
miR-520c | -2.23 | 3.85E-02 | 19q13.42 | |
13q(del) (n = 6) | miR-221 | -9.71 | 1.18E-04 | Xp11.3 |
miR-222 | -9.50 | 1.78E-03 | Xp11.3 | |
let-7b | -5.15 | 3.38E-03 | 22q13.31 | |
let-7a | -4.92 | 3.72E-03 | 9q22.32/11q24.1 | |
let-7c | -4.86 | 6.70E-03 | 21q21.1 | |
miR-15a | -4.42 | 6.39E-03 | 13q14 | |
miR-20a | -4.41 | 1.47E-03 | 13q31 | |
miR-107 | -4.40 | 3.23E-03 | 10q23.31 | |
miR-26a | -4.37 | 3.26E-03 | 3p22.2/12q14.1 | |
miR-103 | -4.30 | 8.98E-03 | 5q34/20p13 | |
miR-142 | -4.13 | 1.15E-03 | 17q22 | |
miR-195 | -3.97 | 6.98E-03 | 17p13.1 | |
miR-146a | -3.92 | 1.46E-03 | 5q33.3 | |
miR-23a | -3.80 | 6.44E-03 | 19p13.12 | |
miR-92a | -3.77 | 3.57E-03 | 13q31 | |
miR-27a | -3.58 | 2.25E-03 | 19p13.12 | |
miR-361 | -3.46 | 4.19E-03 | Xq21.2 | |
miR-145 | -3.43 | 7.10E-03 | 5q32 | |
miR-92b | -3.37 | 9.82E-03 | 13q31 | |
miR-19a | -3.36 | 5.57E-03 | 13q31 | |
miR-199a* | -2.93 | 5.93E-03 | 19p13.2/1q24.3 | |
miR-34a | -2.89 | 2.56E-03 | 1p36.22 | |
miR-188 | -2.79 | 8.43E-03 | Xp11.23 | |
miR-196a | -2.40 | 5.60E-03 | 17q21.32 | |
miR-485 | -2.33 | 4.18E-03 | 19q13.42 | |
miR-16 | -2.23 | 7.79E-03 | 13q14 | |
miR-493 | -1.89 | 2.46E-03 | 14q32.2 |