Figure 2

A single event of normal bone remodeling initiated by a momentary perturbation of the osteoclast nontrivial steady state population by an increase of 10 cell units. System of equations (1): The osteoclast population first decreases with a consequent increase in osteoblast population and a resorption of bone mass, followed by a return to steady-state levels. The blue line represents the steady-state solution. The parameters are α₁ = 3.0, α₂ = 4.0, β₁ = 0.2, β₂ = .02, g₁₁ = .5, g₂₂ = 0.0, g₁₂ = 1.0, and g₂₁ = -0.5. The nontrivial steady state with these parameters is = 1.06 and = 212.13. The initial conditions are C(0) = 11.06 and B(0) = 212.13. The bone mass parameters are k₁ = .24, k₂ = .0017, as in [22].