Figure 5From: A theoretical quantitative model for evolution of cancer chemotherapy resistanceGrowth pattern of a tumor treated with maximum tolerated dose at generation 45. Growth pattern of a tumor treated with maximum tolerated dose at generation 45. A represents chemoresistance (red resistant and green sensitive), B represents hyperglycolysis (red high glycolysis and green low), C shows acid resistance (red resistant to low pHe and green sensitive) and D shows quiescent cells (green) and proliferative (yellow). Despite being 10 times smaller than the original tumor, it is entirely composed of chemoresistant cells (red) and will not respond to therapy.Back to article page