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Figure 6 | Biology Direct

Figure 6

From: CD44 expression positively correlates with Foxp3 expression and suppressive function of CD4+ Treg cells

Figure 6

Intracelluler IL-10 levels in T reg cells of thymocytes and splenocytes. Splenocytes (A and B) and thymocytes (C and D) were obtained from naïve C57BL/6 mice, stained with mAbs against CD4 (PE-Cy7), CD8 (FITC), CD44 (PE), CD25 (APC-Alexa Fluor755), Foxp3 (APC) and IL-10 (PerCP), and analyzed by flow cytometry. (A and C) The percentages of IL-10+ cells in CD4+CD25+CD44- and CD4+CD25+CD44+ cells. (B and D) The percentages of IL-10+ cells in CD4+CD25+CD44-FoxP3+ and CD4+CD25+CD44+ FoxP3+ cells. Shown are representative results from one of four independent experiments. Data in B and D are presented as mean ± S.D.

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Biology Direct

ISSN: 1745-6150

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