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Figure 3 | Biology Direct

Figure 3

From: Multipotent adult germ-line stem cells, like other pluripotent stem cells, can be killed by cytotoxic T lymphocytes despite low expression of major histocompatibility complex class I molecules

Figure 3

Histology of teratomas formed after injection of maGSC Stra8 SSC5 cells and differentiated cells into immunodeficient SCID/beige mice. (A-C) Histological analysis of a representative teratoma derived from maGSC Stra8 SSC5 cells under condition I. (D-F) Histology of a teratoma derived from in vitro differentiated cells. The formed teratomas contained derivatives of all three embryonic germ layers (ectoderm, mesoderm, and endoderm). (A, D) Gut epithelium (endoderm). (A) Cartilage at arrow (mesoderm). (B, E) A rivulet of muscle at arrow (mesoderm). (C, F) Neural-like tissues at arrow (ectoderm). All images were obtained from formalin-fixed and paraffin-embedded teratoma sections stained with hematoxylin and eosin.

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