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Figure 1 | Biology Direct

Figure 1

From: Prokaryotic homologs of Argonaute proteins are predicted to function as key components of a novel system of defense against mobile genetic elements

Figure 1

Domain architecture variation in homologs of Argonaute from prokaryotes (pAgos) and eukaryotes (Ago). Structural domains (N-term, L1, PAZ, L2, Mid, PIWI) are projected from the tertiary structure of AaAgo (pdb: 1YVU[35]). Red bars show the inactivated catalytic sites of PIWI domain. Sir2, predicted Sir2 family nuclease domain. APAZ, a domain identified in this work that is associated with pAgos. The domains are shown roughly to scale.

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Biology Direct

ISSN: 1745-6150

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