Table 2 The pairs of amino acids that show the highest negative impact on the standard code fitness
PRS | Gilis score matrix | Average | ||||||
|---|---|---|---|---|---|---|---|---|
Arg | Cys | -1.00 | Arg | Gly | -1.00 | Arg | Trp | -0.70 |
Arg | Trp | -0.82 | Leu | Phe | -1.00 | His | Tyr | -0.60 |
His | Leu | -0.66 | Ala | Thr | -0.93 | Arg | Gly | -0.54 |
Asn | Tyr | -0.52 | Arg | Ser | -0.71 | Leu | Phe | -0.50 |
His | Tyr | -0.49 | Asn | Lys | -0.71 | Arg | Cys | -0.50 |
Glu | Lys | -0.31 | Asp | Glu | -0.71 | Ala | Thr | -0.47 |
Lys | Thr | -0.18 | Gln | His | -0.71 | Arg | Ser | -0.43 |
Leu | Pro | -0.16 | His | Tyr | -0.71 | Glu | Lys | -0.41 |
Arg | Ser | -0.14 | Ile | Met | -0.57 | Asp | Glu | -0.36 |
Phe | Ser | -0.13 | Arg | Trp | -0.57 | Gln | His | -0.36 |
Gln | Lys | -0.12 | Glu | Lys | -0.50 | Asn | Lys | -0.36 |
Ala | Val | -0.11 | Asn | Asp | -0.43 | His | Leu | -0.33 |
Lys | Met | -0.11 | Leu | Val | -0.43 | Ile | Met | -0.29 |
Gly | Trp | -0.09 | Ala | Ser | -0.36 | Leu | Val | -0.23 |
Met | Thr | -0.09 | Pro | Ser | -0.29 | Asn | Tyr | -0.19 |