Figure 13

Endocytosis of the tight junction. Protruding fingers, P, are formed between neighbouring cells at the tight junction. Pinching protrusions, PP, of double plasma membranes from opposing cells are frequently associated with necks, N, that contain electron dense materials. Endocytosed junctions, EJ, have double plasma membranes and broken necks, BN. Arrows mark the characteristic tight junction membrane kisses. Scale bar, 100 nm.