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Table 1 Overrepresented GO terms from genes with TE-derived HS sites

From: Transposable element derived DNaseI-hypersensitive sites in the human genome

Clusters 1 GO id 2 GO level 3 GO name 4 Counts 5 P-values6
Immune response group
2 GO:0009607 4 response to biotic stimulus 21 4.9 × 10-7
25     8 1.7 × 10-2
2 GO:0006952 5 defense response 20 1.0 × 10-6
25     8 1.6 × 10-2
2 GO:0006955 6 immune response 20 3.6 × 10-7
25     8 1.3 × 10-2
2 GO:0051707 5 response to other organism 11 1.8 × 10-4
25     5 3.3 × 10-2
2 GO:0009613 6 response to pest, pathogen or parasite 11 1.0 × 10-4
25     5 2.7 × 10-2
2 GO:0030098 9 lymphocyte differentiation 3 6.2 × 10-3
19     3 1.6 × 10-2
Regulation group
15 GO:0050789 2 regulation of biological process 40 4.4 × 10-8
25     17 7.5 × 10-3
15 GO:0050794 3 regulation of cellular process 39 2.2 × 10-8
25     17 4.1 × 10-3
15 GO:0050791 3 regulation of physiological process 38 2.2 × 10-8
25     15 1.3 × 10-6
15 GO:0051244 4 regulation of cellular physiological process 38 1.3 × 10-8
25     15 1.3 × 10-2
Metabolism group
15 GO:0050875 3 cellular physiological process 73 6.5 × 10-4
19     88 3.8 × 10-3
15 GO:0044238 4 primary metabolism 63 1.7 × 10-6
19     67 4.8 × 10-3
15 GO:0044237 4 cellular metabolism 63 9.0 × 10-6
19     71 1.3 × 10-3
9 GO:0043170 4 macromolecule metabolism 26 2.8 × 10-2
15     37 2.0 × 10-2
19     50 9.1 × 10-4
9 GO:0043283 5 biopolymer metabolism 18 2.8 × 10-2
15     30 8.0 × 10-5
19     35 5.1 × 10-4
Cell death group
2 GO:0043067 6 regulation of programmed cell death 7 7.8 × 10-3
19     7 3.7 × 10-2
2 GO:0042981 7 regulation of apoptosis 7 7.8 × 10-3
19     7 3.7 × 10-2
  1. 1Gene coexpression, based on k-means analysis, cluster identifier.
  2. 2Biological process Gene Ontology (GO) annotation term.
  3. 3Hierarchical level (descending from 1) in the biological process GO directed acyclic graph.
  4. 4Name assigned to the GO term
  5. 5Number of genes in each cluster associated with the GO term.
  6. 6P-value associated with the over-representation of the GO term in each cluster