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Figure 4 | Biology Direct

Figure 4

From: Distinguishing HIV-1 drug resistance, accessory, and viral fitness mutations using conditional selection pressure analysis of treated versus untreated patient samples

Figure 4

Independent HIV-1 datasets yield reproducible positive selection results. Our method identified positively selected sites (marked with different symbols depending on whether the site is a known drug resistance mutation, accessory mutation, etc.) in independent analyses of four different datasets: Specialty: 48,387 U.S. patient samples, a mix of treated and untreated patients; Stanford-Treated: 1797 U.S. patient samples with specific drug treatments; Stanford-Untreated: 2628 U.S. untreated patient samples; African: 399 African patient samples, HIV-1 subtype C (predominantly untreated patients).

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Biology Direct

ISSN: 1745-6150

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